Methyl salicylate material safety data sheet cas no 119368. Methyl salicylate functions as a flavouring agent in chewing gums, syrups and ice creams. Synthetic methyl salicylate and that from betula lenta usp methyl salicylate rs are optically inactive. S80082, s93305, nc9972460, o3695 500, o3695500, o3695500, xxo3695et500 synonyms. Methyl salicylate type of posting revision bulletin posting. The conjugate base of any of the four isomers of methylsalicylic acid. Ethyl salicylate material safety data sheet cas no. This material is provided for educational purposes only. Salicylate, the esters capryloyl salicylic acid, c1215 alkyl salicylate, isocetyl salicylate, isodecyl salicylate, methyl salicylate, myristyl salicylate, myristyl salicylate, ethylhexyl salicylate, and tridecyl salicylate, and the compounds butyloctyl salicylate and hexyldodecyl salicylate are safe as used when formulated to avoid irritation. Product and company identification methyl salicylate synonymsgeneral names. Ethyl salicylate cas no 118616 material safety data sheet sds msds section 1. Methyl salicylate material safety data sheet cas no. Fisher scientific 1 reagent lane fair lawn, nj 07410 for information, call. Amended safety assessment of salicylic acid and salicylates.
Methyl salicylate, synthetic created by global safety management, inc. Use of this measured proportion of eaters in place of the default assumption of 10% yields an estimated intake of methyl salicylate of 0. Synthesis of methyl salicylate via amine diazotization important references. Identification of the substancemixture and of the supplier. Reregistration eligibility decision for methyl salicylate.
Safety data sheet southwest tennessee community college. Methyl salicylate type of posting revision bulletin. Use of the information, documents and data from the echa website is subject to the. If seeking medical attention, provide sds document to physician. The format of the safety data sheet is defined in the reach regulation. When heated to decomposition, the smoke from burning essential oils may contain potential carcinogens, such as polycyclic aromatic hydrocarbons pahs. Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. A toxicologic and dermatologic assessment of salicylates. Simultaneous analytical method development and validation. If you are 60 or older, use methyl salicylate and menthol cream and ointment with care. An ester compromises an organic or inorganic acid in which one or more hydroxy oh groups have been replaced by and alkoxy oalkyl group. Central drug house p ltd 728 vardaan house new delhi2 india. Treatment, storage, transportation and disposal must be in accordance with federal, stateprovincial and local regulations. Methyl salicylate has been used in the hyalinization of tissues for pulmonary angiography.
Cool, rinse the condenser and the sides of the flask with a few ml of water, add phenolphthalein ts, and titrate the excess alkali with 1 n sulfuric acid vs. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Identification of the substancemixture and of the companyundertaking 1. Salicylic acid and salicylates as used in cosmetics. Evaluate for hypoglycemia, electrolyte imbalances, and hypoxia.
Methyl salicylate c8h8o3 cid 43 structure, chemical names, physical and. Methyl salicylate pesticide chemical code 076601 is the major constituent of oil of wintergreen which is a natural fragrant oil. If methyl salicylate and menthol cream and ointment is swallowed, call a doctor or poison control center right away. Methyl salicylate 119368 safety data sheet methyl salicylate page 2 of 10 p501. Sodium methyl paraben safety data sheet according to federal register vol. Section 1 chemical product and company identification. Material safety data sheet chandlergilbert community. The recovery was calculated by standard addition method. Physicians should be aware of the potential risks of salicylate dermal absorption and toxicity. Essential oils are naturally high in volatile organic compounds vocs.
Dailymed antiseptic eucalyptol, menthol, methyl salicylate. It has a role as a flavouring agent, a metabolite and an insect attractant. Revision bulletin 2 methyl official august 1, 2017 optical rotation. It has counter irritant and antiinflammatory effects. Persons with disabilities having problems accessing the pdf files below may call 301 7963634 for assistance. Assay place about 2 g of methyl salicylate, accurately weighed, in a flask, add 40. If in scope, these drugs will include rxnorm normal forms when editing. Salicylic acid, the salts calcium salicylate, magnesium salicylate, mea salicylate, potassium salicylate, sodium salicylate, and tea salicylate.
Lists the various brand names available for medicines containing methyl salicylate. Files are available under licenses specified on their description page. Methyl salicylate oil of wintergreen or wintergreen oil is an organic ester. Material safety data sheet page 1 of 2 methyl salicylate. Methyl salicylate, the methyl ester of salicylic acid. It is a benzoate ester and a member of salicylates. One volume of natural methyl salicylate dissolves tailing factor. Methyl salicylate is a critical mobile signal for plant systemic acquired resistance article pdf available in science 3185847. Antiseptic mouth rinse eucalyptol, menthol, methyl. First aid measures always seek professional medical attention after first aid measures are provided. Find support for a specific problem on the support section of our website. Synthesis of methyl salicylate from aspirin esters are a class of organic compounds.
Apr 24, 2019 for the temporary relief of minor aches and pains of muscles and joints, such as simple backache, lumbago, arthritis, neuralgia, strains, bruises, and sprains. Methyl salicylate is fully degradation biodegradable. For active bleeding or coagulation disorders, give. Renal dialysis patients are at increased risk for salicylism because salicylates are primarily excreted by the kidneys. According to the united states pharmacopeia 1 methyl salicylate oil of gaultheria, oil of wintergreen, oil of betula or oil of sweet birch is a colorless, yellowish or reddish liquid having the characteristic odor. Methyl salicylate from gaultheria usp methyl salicylate. Salicylate toxicity from ingestion and continued dermal. Ac127680000, ac127680010, ac127680050, ac220490000, ac220490010, ac220490025 ac220490025, ac220490050, ac220495000 synonyms. Methyl salicylate oil of wintergreen or wintergreen oil is an organic compound with the formula c 6 h 4 ohco 2 ch 3. Safety data sheet according to 29cfr19101200 and ghs rev. Chronic dermal application of some salicylate containing products can produce systemic salicylate toxicity. Material safety data sheet salicylic acid section 1 chemical product and company identification msds name. The use of methyl salicylate as a topical medical product is subject to a 2 in japan, methyl s alicylate which conforms to the standards of the japanese standards of cosmetic ingredients jsci has precedent for use at a maximum concentration of 0. Methyl salicylate is found in trees, legumes and exotic plants.
Hazardous in case of skin contact irritant, of eye contact irritant. Salicylate toxicity from percutaneous absorption can occur, especially with methyl salicylate. A larger size patch 10 cm x 14 cm, with the same ingredients, was approved on november 5, 2012 for the same. Suspected of damaging fertility or the unborn child.
It is a colorless, viscous liquid with a sweet, fruity odor reminiscent of root beer, but often associatively called minty, as it is an ingredient in mint candies. Methyl salicylate from gaultheria usp methyl salicylate related compound a rs procumbens is slightly levorotatory, the angular rotation. Sep 10, 2012 antiseptic eucalyptol, menthol, methyl salicylate, thymol mouthwash if this spl contains inactivated ndcs listed by the fda initiated compliance action, they will be specified as such. Sigmaaldrich offers a number of methyl salicylate products. Do not give methyl salicylate and menthol cream and ointment to a child younger than 12 years old without first checking with the doctor. The use of methyl salicylate as a topical medical product is subject to a 2 in japan, methyl s alicylate which conforms to the standards of the japanese standards of cosmetic ingredients jsci has. All structured data from the file and property namespaces is available under the. Identification of the substancemixture and of the company undertaking 1. Safety data sheet methyl salicylate page 3 of 10 need for endotracheal intubation. Nmethyl dialkanol amine and oleic fatty acid diacid copolymer, methyl quaternised.
The product chemistry data requirements for methyl salicylate are fully satisfied. This file is licensed under the creative commons attributionshare alike 3. Methyl salicylate cas no 119368 material safety data. Methyl salicylate may be used as an analytical reference standard for the quantification of the analyte in ulmus pumila leaves using gas chromatography coupled to mass spectrometry gcms. Sds of methyl salicylate, safety data sheets, cas 119368.